ZFIN ID: ZDB-GENE-980526-423
Gene Name: forkhead box A3
Gene Symbol: foxa3    Nomenclature History

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Previous Names: fa11c04, fc37a08, fkd2 (1), forkhead-2, wu:fa11c04, wu:fc37a08, zf-FKH1, Zffkh1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including axial mesoderm morphogenesis; hatching gland development; and nervous system development. Localizes to nucleus. Is expressed in several structures, including axial mesoderm; digestive system; endoderm; germ ring; and hatching gland. Orthologous to human FOXA3 (forkhead box A3).
Genome Resources: Alliance (1),  Gene:30559 (1),  Ensembl(GRCz11):ENSDARG00000012788 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb162 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb163 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • la013319Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-foxa3 1
    CRISPR2-foxa3
    2
    MO1-foxa3 N/A 3
    MO2-foxa3 N/A 1
    DISEASE ASSOCIATED WITH foxa3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH foxa3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axial mesoderm morphogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA foxa3-201 (1)    Ensembl 2763
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-foxa3 polyclonal Rabbit IHC 2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM foxa3 No data available
    MARKER RELATIONSHIPS
    foxa3 Contained in: [BAC] DKEY-223N17 (1) (order this)
    foxa3 Encodes: [EST] fa11c04, fc37a08
    [cDNA] MGC:194053 (1), MGC:194065 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131299 (1) 2524 nt
    Genomic GenBank:BX908751 (1) 157961 nt
    Select Tool
    Polypeptide UniProtKB:B3DGF9 (1) 441 aa
    Sequence Information (all 24)
    ORTHOLOGY for foxa3 ( Chr: 18 )
    CITATIONS (232)