Gene

sox11a

ID
ZDB-GENE-980526-395
Name
SRY-box transcription factor 11a
Symbol
sox11a Nomenclature History
Previous Names
  • cb237 (1)
  • etID309973.17 (1)
  • id:ibd2104 (1)
  • wu:fb16g02 (1)
  • zgc:136533
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in brain development; camera-type eye development; and negative regulation of smoothened signaling pathway. Predicted to localize to nuclear transcription factor complex. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 27. Is expressed in several structures, including mesoderm; nervous system; neural keel; neural rod; and somite. Orthologous to human SOX11 (SRY-box transcription factor 11).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
35 figures from 13 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sox11a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Coffin-Siris syndrome 9 Alliance Coffin-Siris syndrome 9 615866
Associated With sox11a Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009071 High mobility group box domain
Family IPR017386 Transcription factor SOX-12/11/4
Family IPR029551 Transcription factor SOX-11
Homologous_superfamily IPR036910 High mobility group box domain superfamily
Domain Details Per Protein
Protein Length High mobility group box domain High mobility group box domain superfamily Transcription factor SOX-11 Transcription factor SOX-12/11/4
UniProtKB:Q9YH23 354
UniProtKB:Q9I9C8 354
UniProtKB:Q1RM26 336
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations