Gene

snap25b

ID
ZDB-GENE-980526-392
Name
synaptosome associated protein 25b
Symbol
snap25b Nomenclature History
Previous Names
  • snap25.2 (1)
  • wu:fj33h05
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have SNAP receptor activity and syntaxin-1 binding activity. Involved in clustering of voltage-gated sodium channels and locomotory behavior. Predicted to colocalize with BLOC-1 complex. Is expressed in nervous system. Human ortholog(s) of this gene implicated in Down syndrome and congenital myasthenic syndrome 18. Orthologous to human SNAP25 (synaptosome associated protein 25).
Genome Resources
Note
None
Expression
All Expression Data
16 figures from 7 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Moravec et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With snap25b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital myasthenic syndrome 18 Alliance ?Myasthenic syndrome, congenital, 18 616330
Associated With snap25b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000727 Target SNARE coiled-coil homology domain
Domain IPR000928 SNAP-25 domain
Family IPR039077 Synaptosomal-associated protein 25
Domain Details Per Protein
Protein Length SNAP-25 domain Synaptosomal-associated protein 25 Target SNARE coiled-coil homology domain
UniProtKB:A0A2U3TW29 202
UniProtKB:Q6PC54 203
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations