ZFIN ID: ZDB-GENE-980526-364
Gene Name: even-skipped homeobox 1
Gene Symbol: evx1    Nomenclature History

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Previous Name: cb416 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Involved in embryonic skeletal joint development; fin morphogenesis; and ventral spinal cord interneuron specification. Predicted to localize to nucleus. Is expressed in several structures, including central nervous system; fin; gut; neural tube; and pronephros. Orthologous to human EVX1 (even-skipped homeobox 1).
Genome Resources: Alliance (1),  Gene:30499 (1),  Ensembl(GRCz11):ENSDARG00000099365 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
i232 Point Mutation Exon 2 Premature Stop ENU
la020638Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36819 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-evx1 N/A 1
    DISEASE ASSOCIATED WITH evx1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH evx1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ventral spinal cord interneuron specification (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA evx1-201 (1)    Ensembl 2035
    evx1-203 (1)    Ensembl 2398
    evx1-204 (1)    Ensembl 2444
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM evx1
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(evx1-Mmu.Fos:GAL4-VP16,UAS:EGFP) evx1UAS EGFPGAL4VP16 Danio rerioMus musculus 1 1
    Tg(evx1:EGFP) evx1 EGFP Danio rerio 1 2
    MARKER RELATIONSHIPS
    evx1 Contained in: [BAC] DKEY-25E11 (1) (order this)
    evx1 Encodes: [EST] cb416 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131249 (1) 2463 nt
    Genomic GenBank:CR382300 (1) 202006 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IVI8 (1) 377 aa
    Sequence Information (all 21)
    ORTHOLOGY for evx1 ( Chr: 19 )
    CITATIONS (66)