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Gene

pou3f3a

ID
ZDB-GENE-980526-220
Name
POU class 3 homeobox 3a
Symbol
pou3f3a Nomenclature History
Previous Names
  • pou12
  • brn1.1
  • wu:fc33a11
  • zp12
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within brain development and regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in central nervous system; neural tube; neurons; pharyngeal arch; and pronephric duct. Orthologous to human POU3F3 (POU class 3 homeobox 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pou3f3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Snijders Blok-Fisher syndrome 618604
Associated With pou3f3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR000327 POU-specific domain
Domain IPR001356 Homeobox domain
Domain IPR013847 POU domain
Family IPR016362 POU-domain transcription factor, class 3
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Homologous_superfamily IPR010982 Lambda repressor-like, DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Lambda repressor-like, DNA-binding domain superfamily POU domain POU-domain transcription factor, class 3 POU-specific domain
UniProtKB:P56224 438
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations