ZFIN ID: ZDB-GENE-980526-220
Gene Name: POU class 3 homeobox 3a
Gene Symbol: pou3f3a    Nomenclature History

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Previous Names: pou12, brn1.1, wu:fc33a11, zp12

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in central nervous system; neural tube; neurons; pharyngeal arch; and pronephric duct. Orthologous to human POU3F3 (POU class 3 homeobox 3).
Genome Resources: Alliance (1),  Gene:30386 (1),  Ensembl(GRCz11):ENSDARG00000042032 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027108Tg Transgenic Insertion Unknown Unknown DNA
sa38722 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pou3f3a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Snijders Blok-Fisher syndrome 618604
    DISEASE ASSOCIATED WITH pou3f3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process brain development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pou3f3a-201 (1)    Ensembl 2747
    pou3f3a-202 (1)    Ensembl 2891
    pou3f3a-203 (1)    Ensembl 2959
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pou3f3a No data available
    MARKER RELATIONSHIPS
    pou3f3a Contained in: [BAC] DKEYP-118H3 (1)
    pou3f3a Encodes: [EST] fc33a11
    [cDNA] MGC:55267 (1), MGC:65765 (1), MGC:76858 (1), MGC:85606 (1), MGC:192422 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131150 (1) 2189 nt
    Genomic GenBank:BX842683 (1) 160823 nt
    Select Tool
    Polypeptide UniProtKB:P56224 (1) 438 aa
    Sequence Information (all 36)
    ORTHOLOGY for pou3f3a ( Chr: 9 )
    CITATIONS (37)