Gene

glra2

ID

ZDB-GENE-090407-1

Name

glycine receptor, alpha 2

Symbol

glra2 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Exhibits extracellularly glycine-gated ion channel activity. Predicted to be involved in chloride transport and ion transmembrane transport. Predicted to localize to several cellular components, including chloride channel complex; integral component of plasma membrane; and postsynaptic membrane. Is expressed in dorsal telencephalon; hindbrain; spinal cord; and ventral telencephalon. Orthologous to human GLRA2 (glycine receptor alpha 2).

Genome Resources

Note

None

Expression

All Expression Data

6 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Pilorge et al., 2016
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With glra2 Human Ortholog

No data available

Associated With glra2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018000	Neurotransmitter-gated ion-channel, conserved site
Domain	IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
Domain	IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain
Family	IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha
Family	IPR006201	Neurotransmitter-gated ion-channel
Family	IPR008127	Glycine receptor alpha
Homologous_superfamily	IPR036719	Neurotransmitter-gated ion-channel transmembrane domain superfamily
Homologous_superfamily	IPR036734	Neurotransmitter-gated ion-channel ligand-binding domain superfamily