ZFIN ID: ZDB-GENE-090312-136
Gene Name: ATPase H+ transporting accessory protein 1a
Gene Symbol: atp6ap1a    Nomenclature History

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Previous Name: si:ch211-117k14.5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have proton-transporting ATP synthase activity, rotational mechanism and proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in regulation of cellular pH. Predicted to localize to plasma membrane proton-transporting V-type ATPase complex. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human ATP6AP1 (ATPase H+ transporting accessory protein 1).
Genome Resources: Alliance (1),  Gene:100004566 (1),  Ensembl(GRCz11):ENSDARG00000041417 (2)
GENE EXPRESSION
All Expression Data: Fig. S1 from Gokey et al., 2015
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH atp6ap1a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Immunodeficiency 47 300972
DISEASE ASSOCIATED WITH atp6ap1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proton transmembrane transport (more)
Cellular Component integral component of membrane (more)
Molecular Function proton-transporting ATPase activity, rotational mechanism (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA atp6ap1a-201 (1)    Ensembl 3578
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM atp6ap1a No data available
MARKER RELATIONSHIPS
atp6ap1a Contained in: [BAC] CH211-117K14 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_001338976 (1) 3599 nt
Genomic GenBank:CR354596 (1) 172749 nt
Select Tool
Polypeptide UniProtKB:A7MBP9 (1) 469 aa
Sequence Information (all 13)
ORTHOLOGY for atp6ap1a ( Chr: 23 )
CITATIONS (15)