Gene

knstrn

ID
ZDB-GENE-081022-187
Name
kinetochore localized astrin (SPAG5) binding protein
Symbol
knstrn Nomenclature History
Previous Names
  • zgc:195152 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to be involved in mitotic sister chromatid segregation; regulation of attachment of spindle microtubules to kinetochore; and spindle organization. Predicted to act upstream of or within chromosome segregation. Predicted to be active in kinetochore and microtubule cytoskeleton. Human ortholog(s) of this gene implicated in actinic keratosis and skin squamous cell carcinoma. Orthologous to human KNSTRN (kinetochore localized astrin (SPAG5) binding protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With knstrn Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Roifman-Chitayat syndrome, digenic 613328
Associated With knstrn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR033373 Small kinetochore-associated protein
Domain Details Per Protein
Protein Length Small kinetochore-associated protein
UniProtKB:B3DIM7 197
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations