ZFIN ID: ZDB-GENE-070720-10
Gene Name: gastric inhibitory polypeptide
Gene Symbol: gip    Nomenclature History

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Previous Name: zgc:165349

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Exhibits glucagon receptor binding activity. Involved in response to starvation. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Is expressed in endocrine pancreas; intestine; and pancreas. Orthologous to human GIP (gastric inhibitory polypeptide).
Genome Resources: Alliance (1),  Gene:790901 (1),  Ensembl(GRCz11):ENSDARG00000071306 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH gip HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH gip VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to starvation (more)
Cellular Component cellular_component (more)
Molecular Function glucagon receptor binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR039078 Gastric inhibitory polypeptide
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA gip-201 (1)    Ensembl 551
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-gip polyclonal Rabbit IHC 1
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM gip No data available
MARKER RELATIONSHIPS
gip Contained in: [BAC] CH211-51N14 (1), DKEY-220F10 (1) (order this)
gip Has Artifact: [cDNA] MGC:165349 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001080059 (1) 552 nt
Genomic GenBank:CR383677 (1) 164387 nt
Select Tool
Polypeptide UniProtKB:A1DPK4 (1) 112 aa
Sequence Information (all 10)
ORTHOLOGY for gip ( Chr: 12 )
CITATIONS (20)