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ZIRC
ZFIN ID: ZDB-GENE-070424-59
Gene Name: immunoglobin superfamily, member 21b
Gene Symbol: igsf21b    Nomenclature History

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Previous Name: zgc:162186

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have cell adhesion molecule binding activity; protein homodimerization activity; and signaling receptor activity. Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to localize to the cell-cell adherens junction. Is expressed in central nervous system and retina. Orthologous to human IGSF21 (immunoglobin superfamily member 21).
Genome Resources: Alliance (1),  Gene:567714 (1),  Ensembl(GRCz11):ENSDARG00000056084 (2)
GENE EXPRESSION
All Expression Data: 9 figures from 2 publications
Directly Submitted Expression Data: 7 figures (7 images) from Thisse et al., 2008 [cssl:d188]
Wild-type Stages, Structures: Pharyngula:High-pec (42.0h-48.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022545Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa124 Point Mutation Unknown Unknown ENU
    sa1517 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45797 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH igsf21b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH igsf21b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (more)
    Cellular Component adherens junction (more)
    Molecular Function protein binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA igsf21b-201 (1)    Ensembl 2330
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-igsf21b monoclonal Mouse IHC Wright Lab
    1
    CONSTRUCTS WITH SEQUENCES FROM igsf21b No data available
    MARKER RELATIONSHIPS
    igsf21b Contained in: [BAC] CH211-145D10 (1) (order this), DKEY-1C11 (1) (order this)
    igsf21b Encodes: [cDNA] cssl:d188 (1) (order this), MGC:162186 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001110473 (1) 2336 bp
    Genomic GenBank:CR847529 (1) 158776 bp
    Select Tool
    Polypeptide UniProtKB:A4IG39 (1) 473 aa
    Sequence Clusters UniGene:85351 (1)
    Sequence Information (all 17)
    ORTHOLOGY for igsf21b ( Chr: 23 )
    CITATIONS (29)