ZFIN ID: ZDB-GENE-070117-2501
Gene Name: SEC24 homolog D, COPII coat complex component
Gene Symbol: sec24d    Nomenclature History

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Previous Names: bul, bulldog (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have zinc ion binding activity. Involved in cartilage morphogenesis; embryonic viscerocranium morphogenesis; and extracellular matrix constituent secretion. Predicted to localize to COPII vesicle coat. Is expressed in several structures, including immature eye; myotome; nervous system; notochord; and pharyngeal arch cartilage. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Orthologous to human SEC24D (SEC24 homolog D, COPII coat complex component).
Genome Resources: Alliance (1),  Gene:553407 (1),  Ensembl(GRCz11):ENSDARG00000045946 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
m137 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m421 Point Mutation Unknown Premature Stop ENU
    m494 Small Deletion Exon 7 Frameshift, Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m606 Point Mutation Unknown Splice Site, Frameshift, Premature Stop ENU
    m757 Point Mutation Unknown Premature Stop ENU
    sa9139 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10908 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18900 Point Mutation Unknown Premature Stop ENU
    sa21148 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34239 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-sec24d N/A 2
    DISEASE ASSOCIATED WITH sec24d HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Cole-Carpenter syndrome Alliance Cole-Carpenter syndrome 2 616294
    DISEASE ASSOCIATED WITH sec24d VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cartilage morphogenesis (more)
    Cellular Component COPII vesicle coat (more)
    Molecular Function zinc ion binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sec24d No data available
    MARKER RELATIONSHIPS No data available
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001177932 (1) 3277 nt
    Genomic GenBank:CABZ01112895 (1) 24787 nt
    Polypeptide UniProtKB:F1QRB4 (1) 1030 aa
    Sequence Information (all 18)
    ORTHOLOGY for sec24d ( Chr: 7 )
    CITATIONS (23)