ZFIN ID: ZDB-GENE-070112-472
Gene Name: ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
Gene Symbol: urad    Nomenclature History

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Previous Names: prhoxnb, zgc:158663

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Exhibits 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity. Predicted to be involved in allantoin biosynthetic process; purine nucleobase metabolic process; and urate catabolic process. Predicted to localize to the peroxisome. Orthologous to human URAD (ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase).
Genome Resources: Alliance (1),  Gene:557735 (1),  Ensembl(GRCz11):ENSDARG00000071579 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10651 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH urad HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH urad VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process allantoin biosynthetic process (more)
    Cellular Component peroxisome (more)
    Molecular Function 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1
    Domain IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
    Homologous_superfamily IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA urad-201 (1)    Ensembl 759
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM urad No data available
    MARKER RELATIONSHIPS
    urad Contained in: [BAC] CH211-140B10 (1)
    urad Encodes: [cDNA] MGC:158663 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080172 (1) 775 bp
    Genomic GenBank:BX571696 (1) 171175 bp
    Select Tool
    Polypeptide UniProtKB:A1L259 (1) 174 aa
    Sequence Information (all 11)
    ORTHOLOGY for urad ( Chr: 24 )
    CITATIONS (19)