Gene

foxp1a

ID
ZDB-GENE-060929-624
Name
forkhead box P1a
Symbol
foxp1a Nomenclature History
Previous Names
  • im:7146611
  • wu:fb97f01
  • zgc:154010
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; esophagus adenocarcinoma; intellectual disability-severe speech delay-mild dysmorphism syndrome; peritonitis; and schizophrenia. Is expressed in ventral wall of dorsal aorta. Orthologous to human FOXP1 (forkhead box P1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Lu et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With foxp1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
intellectual disability-severe speech delay-mild dysmorphism syndrome Alliance Mental retardation with language impairment and with or without autistic features 613670
Associated With foxp1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR030456 Fork head domain conserved site 2
Domain IPR001766 Fork head domain
Domain IPR032354 FOXP, coiled-coil domain
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Fork head domain Fork head domain conserved site 2 FOXP, coiled-coil domain Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q08BX8 433
UniProtKB:F1Q4T2 637
UniProtKB:E9QDU4 162
UniProtKB:A0A2R8Q1R5 638
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations