ZFIN ID: ZDB-GENE-060929-624
Gene Name: forkhead box P1a
Gene Symbol: foxp1a    Nomenclature History

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Previous Names: im:7146611, wu:fb97f01, zgc:154010

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; esophagus adenocarcinoma; intellectual disability-severe speech delay-mild dysmorphism syndrome; peritonitis; and schizophrenia. Orthologous to human FOXP1 (forkhead box P1).
Genome Resources: Alliance (1),  Gene:564127 (1),  Ensembl(GRCz11):ENSDARG00000004843 (2)
GENE EXPRESSION
All Expression Data: Fig. S4 from Lu et al., 2013
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Day 4 (96.0h-120.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014301Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH foxp1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    intellectual disability-severe speech delay-mild dysmorphism syndrome Alliance Mental retardation with language impairment and with or without autistic features 613670
    DISEASE ASSOCIATED WITH foxp1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA foxp1a-201 (1)    Ensembl 1449
    foxp1a-202 (1)    Ensembl 3042
    foxp1a-204 (1)    Ensembl 558
    ncRNA foxp1a-003 (1)    Ensembl 470
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM foxp1a No data available
    MARKER RELATIONSHIPS
    foxp1a Contained in: [BAC] DKEY-260B22 (1) (order this)
    foxp1a Encodes: [EST] fb97f01, IMAGE:7146611 (1)
    [cDNA] MGC:154010 (1), MGC:193059 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001077564 (1) 2631 nt
    Genomic GenBank:CR388366 (1) 107217 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q1R5 (1) 638 aa
    Sequence Information (all 27)
    ORTHOLOGY for foxp1a ( Chr: 23 )
    CITATIONS (25)