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General Information
ZIRC
ZFIN ID: ZDB-GENE-060825-351
Gene Name: Spi-1 proto-oncogene a
Gene Symbol: spi1a    Nomenclature History

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Attributions

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Previous Names: spi1l (1), zgc:152991

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in regulation of myeloid leukocyte differentiation. Predicted to localize to the nucleus. Is expressed in anterior lateral plate mesoderm; intermediate cell mass of mesoderm; kidney; rostral blood island; and yolk. Orthologous to human SPI1 (Spi-1 proto-oncogene).
Genome Resources: Alliance (1),  Gene:751704 (1),  Ensembl(GRCz11):ENSDARG00000067797 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-spi1a N/A 1
MO2-spi1a N/A 2
DISEASE ASSOCIATED WITH spi1a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH spi1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of myeloid leukocyte differentiation (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 9)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA spi1a-201 (1)    Ensembl 2287
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM spi1a No data available
MARKER RELATIONSHIPS
spi1a Contained in: [BAC] CH211-87J1 (1) (order this)
spi1a Encodes: [cDNA] MGC:152991 (1) (order this), MGC:192527 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001045416 (1) 2126 bp
Genomic GenBank:FP102071 (1) 170462 bp
Select Tool
Polypeptide UniProtKB:F1QFB6 (1) 257 aa
Sequence Clusters UniGene:81548 (1)
Sequence Information (all 23)
ORTHOLOGY for spi1a ( Chr: 25 )
CITATIONS (22)