ZFIN ID: ZDB-GENE-060526-121
Gene Name: NIPBL cohesin loading factor a
Gene Symbol: nipbla
Sequence Ontology ID : SO:0000704

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Previous Names: si:ch211-234b6.2 (1), si:ch73-311f13.1

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have chromatin binding activity; involved in several processes, including cellular macromolecule biosynthetic process, digestive tract development, and embryonic morphogenesis; predicted  ...
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Blastula:512-cell (2.75h-3.0h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb274 Small Deletion Exon 3 Unknown CRISPR
ihb275 Indel Unknown Unknown CRISPR
ihb276 Insertion Exon 16 Unknown CRISPR
ihb277 Indel Exon 16 Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • sa1954 Point Mutation Unknown Splice Site ENU
    sa8770 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 2 from Muto et al., 2011
    Observed in:
    DISEASE ASSOCIATED WITH nipbla HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Cornelia de Lange syndrome 1 Cornelia de Lange syndrome 1 122470
    DISEASE ASSOCIATED WITH nipbla VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process digestive tract development (more)
    Cellular Component nucleus (more)
    Molecular Function chromatin binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011989 (1)
  • InterPro:IPR016024 (1)
  • InterPro:IPR024986 (1)
  • InterPro:IPR026003 (1)
  • InterPro:IPR033031 (1)
  • Pfam:PF12765 (1)
  • Pfam:PF12830 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nipbla-201 (1) 8317
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nipbla No data available
    MARKER RELATIONSHIPS
    nipblaContained in: [BAC] CH73-74D12 (1) (order this), CH73-311F13 (1) (order this), CH211-234B6 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001246284 (1)
    Genomic GenBank:BX510907 (1) 154591bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IGM2 (1) 2382aa
    Sequence Clusters UniGene:88335 (1)
    Sequence Information (all 14)
    OTHER nipbla GENE PAGES
  • Alliance (1)
  • Gene:570900 (1)
  • VEGA:OTTDARG00000033046 (1)
  • Ensembl(GRCz11):ENSDARG00000098272 (1)
  • ORTHOLOGY for nipbla (Chr: 5)
    CITATIONS (22)