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ZIRC
ZFIN ID: ZDB-GENE-060503-719
Gene Name: grainyhead-like transcription factor 2b
Gene Symbol: grhl2b
Sequence Ontology ID : SO:0001217

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Attributions

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Previous Names: grhl2, si:dkey-21k18.2

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits transcription regulatory region DNA binding activity. Involved in apoptotic process involved in morphogenesis; inner ear development; and midbrain-hindbrain boundary morphogenesis. Predicted  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36799 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tsu086Gt Transgenic Insertion Unknown Unknown DNA
  • China Zebrafish Resource Center (CZRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH grhl2b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant nonsyndromic deafness 28 Deafness, autosomal dominant 28 608641
    Corneal dystrophy, posterior polymorphous, 4 618031
    Ectodermal dysplasia/short stature syndrome 616029
    DISEASE ASSOCIATED WITH grhl2b VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    autosomal dominant nonsyndromic deafness grhl2btsu086Gt/tsu086Gt(AB) standard conditions Han et al., 2011
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process apoptotic process involved in morphogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function transcription regulatory region DNA binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007604 (1)
  • InterPro:IPR040167 (1)
  • Pfam:PF04516 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA grhl2b-201 (1) 3699
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM grhl2b
    MARKER RELATIONSHIPS
    grhl2b Contained in: [BAC] DKEY-21K18 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001083072 (1) 1786 bp
    Genomic GenBank:BX294657 (1) 124224 bp
    Select Tool
    Polypeptide UniProtKB:F7VJQ5 (1) 601 aa
    Sequence Clusters UniGene:119348 (1)
    Sequence Information (all 12)
    ORTHOLOGY for grhl2b ( Chr: 19 )
    CITATIONS (26)