ZFIN ID: ZDB-GENE-060421-4337
Gene Name: peripheral myelin protein 22b
Gene Symbol: pmp22b
Sequence Ontology ID : SO:0000704

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Previous Names: id:ibd2630, wu:fb81f09, zgc:136919

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to localize to the plasma membrane; orthologous to human PMP22 (peripheral myelin protein 22).
GENE EXPRESSION
Directly Submitted Expression Data: 3 figures (4 images) from Kudoh et al., 2001 [ibd2630]
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pmp22b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease type 1A Charcot-Marie-Tooth disease, type 1A 118220
Charcot-Marie-Tooth disease type 1E Charcot-Marie-Tooth disease, type 1E 118300
Charcot-Marie-Tooth disease type 3 Dejerine-Sottas disease 145900
Guillain-Barre syndrome ?Neuropathy, inflammatory demyelinating 139393
hereditary neuropathy with liability to pressure palsies Neuropathy, recurrent, with pressure palsies 162500
Roussy-Levy syndrome 180800
DISEASE ASSOCIATED WITH pmp22b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process biological_process (more)
Cellular Component integral component of membrane (more)
Molecular Function molecular_function (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003936 (1)
  • InterPro:IPR004031 (1)
  • InterPro:IPR004032 (1)
  • PROSITE:PS01221 (1)
  • PROSITE:PS01222 (1)
  • Pfam:PF00822 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pmp22b-001 (1) 3161
    pmp22b-002 (1) 682
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pmp22b No data available
    MARKER RELATIONSHIPS
    pmp22bContained in: [BAC] CH211-152F22 (1) (order this)
    pmp22bEncodes: [EST] fb81f09, ibd2630 (order this), IMAGE:7036435
    [cDNA] MGC:136919 (1) (order this), MGC:174239 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001040355 (1) 1382bp
    Genomic GenBank:CR293521 (1) 152631bp
    Select Tool
    Polypeptide UniProtKB:Q1RLQ8 (1) 155aa
    Sequence Clusters UniGene:77410 (1)
    Sequence Information (all 18)
    OTHER pmp22b GENE PAGES
  • Alliance (1)
  • Gene:678607 (1)
  • VEGA:OTTDARG00000021849 (1)
  • Ensembl(GRCz11):ENSDARG00000060457 (2)
  • ORTHOLOGY for pmp22b (Chr: 12)
    CITATIONS (17)