Gene

cog4

ID
ZDB-GENE-060312-33
Name
component of oligomeric golgi complex 4
Symbol
cog4 Nomenclature History
Previous Names
  • zgc:136860
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to be involved in Golgi organization; Golgi vesicle prefusion complex stabilization; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to localize to Golgi transport complex. Used to study Saul-Wilson syndrome. Human ortholog(s) of this gene implicated in Saul-Wilson syndrome and congenital disorder of glycosylation type IIj. Is expressed in nervous system; otic epithelium; otic vesicle protrusion; and pharyngeal arch cartilage. Orthologous to human COG4 (component of oligomeric golgi complex 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cog4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital disorder of glycosylation type IIj Alliance Congenital disorder of glycosylation, type IIj 613489
Saul-Wilson syndrome Alliance Saul-Wilson syndrome 618150
Associated With cog4 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013167 Conserved oligomeric Golgi complex, subunit 4
Domain Details Per Protein
Protein Length Conserved oligomeric Golgi complex, subunit 4
UniProtKB:Q29RB1 781
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations