ZFIN ID: ZDB-GENE-051120-117
Gene Name: mitogen-activated protein kinase 10
Gene Symbol: mapk10    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: jnk3 (1), zgc:123234

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have JUN kinase activity. Involved in enteric nervous system development and liver development. Predicted to localize to cytoplasm and nucleus. Is expressed in brain; enteric nervous system; and eye. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma. Orthologous to human MAPK10 (mitogen-activated protein kinase 10).
Genome Resources: Alliance (1),  Gene:569698 (1),  Ensembl(GRCz11):ENSDARG00000102730 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fci200 Small Deletion Exon 4 Frameshift TALEN
la014121Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23859 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-mapk10 N/A 1
    MO2-mapk10 N/A 1
    MO3-mapk10 N/A 1
    TALEN1-mapk10 1
    PHENOTYPE
    Data: 2 figures from Heanue et al., 2016
    Observed in:
    DISEASE ASSOCIATED WITH mapk10 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mapk10 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process enteric nervous system development (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mapk10-201 (1)    Ensembl 1887
    mapk10-203 (1)    Ensembl 1756
    mapk10-206 (1)    Ensembl 1863
    mapk10-207 (1)    Ensembl 861
    mapk10-208 (1)    Ensembl 674
    ncRNA mapk10-006 (1) 1123
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mapk10 No data available
    MARKER RELATIONSHIPS
    mapk10 Contained in: [BAC] CH211-65I12 (1), CH211-233O14 (1)
    mapk10 Encodes: [cDNA] MGC:123234 (1), MGC:162841 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001037701 (1) 1877 nt
    Genomic GenBank:CR354555 (1) 177811 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IKK9 (1) 472 aa
    Sequence Information (all 49)
    ORTHOLOGY for mapk10 ( Chr: 21 )
    CITATIONS (38)