Gene

mapk10

ID
ZDB-GENE-051120-117
Name
mitogen-activated protein kinase 10
Symbol
mapk10 Nomenclature History
Previous Names
  • jnk3 (1)
  • zgc:123234
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable JUN kinase activity. Acts upstream of or within enteric nervous system development and liver development. Predicted to be active in cytoplasm and nucleus. Is expressed in brain; enteric nervous system; and eye. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma. Orthologous to human MAPK10 (mitogen-activated protein kinase 10).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Heanue et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mapk10 Human Ortholog
No data available
Associated With mapk10 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Conserved_site IPR003527 Mitogen-activated protein (MAP) kinase, conserved site
Domain IPR000719 Protein kinase domain
Family IPR008351 Mitogen-activated protein (MAP) kinase, JNK
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Mitogen-activated protein (MAP) kinase, conserved site Mitogen-activated protein (MAP) kinase, JNK Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A0A0R4IB91 433
UniProtKB:A0A0R4IN30 210
UniProtKB:Q32LV0 430
UniProtKB:A0A0R4IKK9 472
UniProtKB:A0A0R4I9H8 384
UniProtKB:A0A0R4IJM3 102
UniProtKB:A4QP40 384
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations