ZFIN ID: ZDB-GENE-050522-235
Gene Name: synuclein, gamma b (breast cancer-specific protein 1)
Gene Symbol: sncgb    Nomenclature History

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Previous Names: Sncg1 (1), sncg, sncga (1), zgc:112131, zSyn-γ1 (1), zSynA (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Involved in dopaminergic neuron differentiation and larval locomotory behavior. Is expressed in basal plate midbrain region; gill; nervous system; testis; and trigeminal placode. Human ortholog(s) of this gene implicated in Lewy body dementia. Orthologous to human SNCG (synuclein gamma).
Genome Resources: Alliance (1),  Gene:553679 (1),  Ensembl(GRCz11):ENSDARG00000109715 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
xu0365Gt Transgenic Insertion Unknown Unknown DNA
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-sncgb N/A 1
MO2-sncgb N/A 1
MO3-sncgb N/A 1
PHENOTYPE
Data: Fig. 6 from Milanese et al., 2012
Observed in:
DISEASE ASSOCIATED WITH sncgb HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH sncgb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dopaminergic neuron differentiation (more)
Molecular Function molecular_function (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-sncgb polyclonal Rabbit WB 1
CONSTRUCTS WITH SEQUENCES FROM sncgb
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(sncgb:GFP) sncgb GFP Danio rerio 1 3
MARKER RELATIONSHIPS
sncgb Encodes: [EST] IMAGE:7159885 (1)
[cDNA] MGC:112131 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001020652 (1)
Polypeptide UniProtKB:A0A2R8RP85 (1) 114 aa
Sequence Information (all 14)
ORTHOLOGY for sncgb ( Chr: 12 )
CITATIONS (23)