Gene
ints11
- ID
- ZDB-GENE-050522-13
- Name
- integrator complex subunit 11
- Symbol
- ints11 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Is predicted to enable endoribonuclease activity, producing 3'-phosphomonoesters. Involved in snRNA processing. Acts upstream of or within regulation of RNA splicing. Orthologous to human INTS11 (integrator complex subunit 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Tao et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001279 | Metallo-beta-lactamase |
| Domain | IPR011108 | Zn-dependent metallo-hydrolase, RNA specificity domain |
| Domain | IPR022712 | Beta-Casp domain |
| Domain | IPR041897 | Integrator complex subunit 11, MBL-fold |
| Homologous_superfamily | IPR036866 | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
Domain Details Per Protein
| Protein | Length | Beta-Casp domain | Integrator complex subunit 11, MBL-fold | Metallo-beta-lactamase | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | Zn-dependent metallo-hydrolase, RNA specificity domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q503E1
|
598 | |||||
|
UniProtKB:E9QFP8
|
545 | |||||
|
UniProtKB:E9QIT1
|
222 | |||||
|
UniProtKB:F1QEY5
|
598 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
ints11-202
(1)
|
1740 nt | |
| mRNA |
ints11-203
(1)
|
937 nt |
Interactions and Pathways
No data available
Plasmids
No data available