Gene

ncapd2

ID
ZDB-GENE-050506-59
Name
non-SMC condensin I complex, subunit D2
Symbol
ncapd2 Nomenclature History
Previous Names
  • cap-d2 (1)
  • im:6902697
  • si:dkey-175g20.1
  • wu:fc13f08
  • wu:fx06e10
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have chromatin binding activity and histone binding activity. Involved in mitotic sister chromatid segregation. Predicted to localize to condensed chromosome, centromeric region. Is expressed in nervous system; optic cup; pectoral fin; pharyngeal arch 3-7 skeleton; and proliferative region. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPD2 (non-SMC condensin I complex subunit D2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Seipold et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ncapd2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Microcephaly 21, primary, autosomal recessive 617983
Associated With ncapd2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR024324 Condensin complex subunit 1, N-terminal
Domain IPR032682 Condensin complex subunit 1, C-terminal
Family IPR007673 Condensin subunit 1
Family IPR026971 Condensin subunit 1/Condensin-2 complex subunit D3
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR016024 Armadillo-type fold
Domain Details Per Protein
Protein Length Armadillo-like helical Armadillo-type fold Condensin complex subunit 1, C-terminal Condensin complex subunit 1, N-terminal Condensin subunit 1 Condensin subunit 1/Condensin-2 complex subunit D3
UniProtKB:A0A0R4IRW7 1404
UniProtKB:A7MCQ4 454
UniProtKB:Q568Q3 531
UniProtKB:Q6IQB9 508
UniProtKB:B0V123 1380
UniProtKB:Q7SXS6 979
UniProtKB:A2RV05 1414
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations