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General Information
ZIRC
ZFIN ID: ZDB-GENE-050420-319
Gene Name: WT1 transcription factor b
Gene Symbol: wt1b
Sequence Ontology ID : SO:0000704

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Previous Names: si:ch211-160j6.3 (1), zgc:152697 (1)

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in glomerular visceral epithelial cell differentiation and pronephros development. Predicted to  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
li14 Small Deletion Exon 2 Unknown CRISPR
ue402 Small Deletion Unknown Frameshift, Premature Stop CRISPR
Targeting reagents:
DISEASE ASSOCIATED WITH wt1b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Denys-Drash syndrome Denys-Drash syndrome 194080
Frasier syndrome Frasier syndrome 136680
malignant mesothelioma Mesothelioma, somatic 156240
nephroblastoma Wilms tumor, type 1 194070
nephrotic syndrome type 4 Nephrotic syndrome, type 4 256370
Meacham syndrome 608978
DISEASE ASSOCIATED WITH wt1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process glomerular visceral epithelial cell differentiation (more)
Cellular Component nucleus (more)
Molecular Function metal ion binding (more)
GO Terms (all 8)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA wt1b-201 (1) 1389
GENE PRODUCT DESCRIPTION No description available
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
MARKER RELATIONSHIPS
wt1bContained in: [BAC] CH211-4L14 (1) (order this), CH211-160J6 (1) (order this)
wt1bEncodes: [cDNA] MGC:152697 (1) (order this), MGC:191893 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001039634 (1) 2221bp
Genomic GenBank:BX248120 (1) 181815bp
Select Tool
Polypeptide UniProtKB:Q1L884 (1) 412aa
Sequence Clusters UniGene:91799 (1)
Sequence Information (all 22)
ORTHOLOGY for wt1b (Chr: 18)
CITATIONS (68)