Gene

gucy1a1

ID
ZDB-GENE-050417-230
Name
guanylate cyclase 1 soluble subunit alpha 1
Symbol
gucy1a1 Nomenclature History
Previous Names
  • gucy1a3
  • im:7136149
  • zgc:112159 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have guanylate cyclase activity and nucleotide binding activity. Involved in inflammatory response to wounding. Predicted to localize to integral component of membrane. Is expressed in diencephalon and floor plate. Human ortholog(s) of this gene implicated in Moyamoya disease. Orthologous to human GUCY1A1 (guanylate cyclase 1 soluble subunit alpha 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gucy1a1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Moyamoya disease Alliance Moyamoya 6 with achalasia 615750
Associated With gucy1a1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site
Domain IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
Domain IPR011645 Haem NO binding associated
Homologous_superfamily IPR029787 Nucleotide cyclase
Homologous_superfamily IPR042463 Haem NO binding associated domain superfamily
Domain Details Per Protein
Protein Length Adenylyl cyclase class-3/4/guanylyl cyclase Adenylyl cyclase class-4/guanylyl cyclase, conserved site Haem NO binding associated Haem NO binding associated domain superfamily Nucleotide cyclase
UniProtKB:E7EZW5 679
UniProtKB:Q567C5 480
UniProtKB:F1QTC8 474
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations