Gene
islr2
- ID
- ZDB-GENE-050320-95
- Name
- immunoglobulin superfamily containing leucine-rich repeat 2
- Symbol
- islr2 Nomenclature History
- Previous Names
-
- zgc:101901
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Involved in retinal ganglion cell axon guidance. Predicted to localize to integral component of membrane. Is expressed in nervous system. Orthologous to human ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2).
- Genome Resources
- Note
- None
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
- IMAGE:7162555 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Panza et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000483 | Cysteine-rich flanking region, C-terminal |
Domain | IPR003598 | Immunoglobulin subtype 2 |
Domain | IPR003599 | Immunoglobulin subtype |
Domain | IPR007110 | Immunoglobulin-like domain |
Domain | IPR013098 | Immunoglobulin I-set |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Repeat | IPR001611 | Leucine-rich repeat |
Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
Domain Details Per Protein
Protein | Length | Cysteine-rich flanking region, C-terminal | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype | Immunoglobulin subtype 2 | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype |
---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A8BBF4
|
567 | ||||||||||
UniProtKB:Q5BL20
|
712 | ||||||||||
UniProtKB:F1QNH9
|
712 |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl