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ZIRC
ZFIN ID: ZDB-GENE-050320-95
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Gene Name: immunoglobulin superfamily containing leucine-rich repeat 2
Gene Symbol: islr2
Sequence Ontology ID : SO:0001217

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Previous Name: zgc:101901

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(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in retinal ganglion cell axon guidance. Predicted to localize to the integral component of membrane. Is expressed in nervous system. Orthologous to several human genes including ISLR2  ...
GENE EXPRESSION
All Expression Data: 9 figures from 3 publications
Directly Submitted Expression Data: 7 figures (16 images) from Thisse et al., 2004 [IMAGE:7162555]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa82 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa24679 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa44307 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH islr2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH islr2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process retinal ganglion cell axon guidance (more)
    Cellular Component integral component of membrane (more)
    Molecular Function protein binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000483 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR003591 (1)
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR032675 (1)
  • InterPro:IPR036179 (1)
  • PROSITE:PS50835 (1)
  • Pfam:PF07679 (1)
  • Pfam:PF13855 (1)
    • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA islr2-201 (1) 3400
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM islr2 No data available
    MARKER RELATIONSHIPS
    islr2 Contained in: [BAC] DKEY-4M3 (1) (order this)
    islr2 Encodes: [EST] IMAGE:7162555 (1) (order this)
    [cDNA] MGC:101901 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001013523 (1) 3422 bp
    Select Tool
    Genomic GenBank:CR855275 (1) 159960 bp
    Select Tool
    Polypeptide UniProtKB:F1QNH9 (1) 712 aa
    Select Tool
    Sequence Clusters UniGene:120799 (1)
    Sequence Information (all 14)
    OTHER islr2 GENE PAGES
  • Alliance (1)
  • Gene:541396 (1)
  • VEGA:OTTDARG00000028423 (1)
  • Ensembl(GRCz11):ENSDARG00000051875 (1)
    • ORTHOLOGY for islr2 ( Chr: 25 )
    CITATIONS (25)