Gene

capn2a

ID
ZDB-GENE-050320-69
Name
calpain 2, (m/II) large subunit a
Symbol
capn2a Nomenclature History
Previous Names
  • zgc:113590
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to cytoplasm. Is expressed in brain; embryonic structure; pectoral fin; and retina. Orthologous to human CAPN2 (calpain 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With capn2a Human Ortholog
No data available
Associated With capn2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR000169 Cysteine peptidase, cysteine active site
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR001300 Peptidase C2, calpain, catalytic domain
Domain IPR002048 EF-hand domain
Domain IPR022682 Peptidase C2, calpain, large subunit, domain III
Domain IPR022683 Peptidase C2, calpain, domain III
Domain IPR033883 Calpain subdomain III
Family IPR022684 Peptidase C2, calpain family
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR036213 Calpain large subunit, domain III superfamily
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length Calpain large subunit, domain III superfamily Calpain subdomain III Cysteine peptidase, cysteine active site EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair Papain-like cysteine peptidase superfamily Peptidase C2, calpain, catalytic domain Peptidase C2, calpain, domain III Peptidase C2, calpain family Peptidase C2, calpain, large subunit, domain III
UniProtKB:Q5BLH5 698
UniProtKB:A0A0R4IFK0 698
UniProtKB:F1QMV0 596
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations