ZFIN ID: ZDB-GENE-050310-5
Gene Name: insulin-like 3 (Leydig cell)
Gene Symbol: insl3    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: rflx (1), rln2, rlnc (1), rlx3c (1), si:rp71-39b20.5 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor binding activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to localize to extracellular space. Is expressed in several structures, including endocrine system; female organism; gut; heart; and male organism. Human ortholog(s) of this gene implicated in cryptorchidism. Orthologous to human INSL3 (insulin like 3).
Genome Resources: Alliance (1),  Gene:563417 (1),  Ensembl(GRCz11):ENSDARG00000035862 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1531 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH insl3 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cryptorchidism Alliance Cryptorchidism 219050
DISEASE ASSOCIATED WITH insl3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (more)
Cellular Component extracellular region (more)
Molecular Function hormone activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA insl3-201 (1)    Ensembl 932
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM insl3 No data available
MARKER RELATIONSHIPS
insl3 Contained in: [BAC] RP71-39B20 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001115053 (1)
Genomic GenBank:BX530024 (1) 146464 nt
Select Tool
Polypeptide UniProtKB:Q2P9V5 (1) 153 aa
Sequence Information (all 16)
ORTHOLOGY for insl3 ( Chr: 2 )
CITATIONS (45)