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General Information
ZIRC
ZFIN ID: ZDB-GENE-050306-26
Gene Name: tryptophanyl tRNA synthetase 2, mitochondrial
Gene Symbol: wars2
Sequence Ontology ID : SO:0001217

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Previous Name: zgc:110828 (1)

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have tryptophan-tRNA ligase activity. Involved in sprouting angiogenesis. Predicted to localize to the mitochondrial matrix. Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2,  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6907795]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa41399 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41400 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH wars2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Neurodevelopmental disorder, mitochondrial, with abnormal movements and lactic acidosis, with or without seizures 617710
    DISEASE ASSOCIATED WITH wars2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process sprouting angiogenesis (more)
    Cellular Component cytosol (more)
    Molecular Function aminoacyl-tRNA ligase activity (more)
    GO Terms (all 13)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wars2-201 (1) 1246
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM wars2 No data available
    MARKER RELATIONSHIPS
    wars2 Contained in: [BAC] CH211-250K6 (1) (order this)
    wars2 Encodes: [EST] IMAGE:6907795 (1) (order this)
    [cDNA] MGC:110828 (1) (order this), MGC:191369 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001013323 (1) 1270 bp
    Genomic GenBank:BX255950 (1) 151210 bp
    Select Tool
    Polypeptide UniProtKB:B0S5M9 (1) 364 aa
    Sequence Clusters UniGene:39146 (1)
    Sequence Information (all 16)
    ORTHOLOGY for wars2 ( Chr: 9 )
    CITATIONS (21)