Gene

gdf9

ID
ZDB-GENE-050221-7
Name
growth differentiation factor 9
Symbol
gdf9 Nomenclature History
Previous Names
  • zgc:123030
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have cytokine activity. Involved in female sex determination. Predicted to localize to extracellular space. Is expressed in fertilized egg; gonad; and immature gonad. Human ortholog(s) of this gene implicated in premature ovarian failure. Orthologous to human GDF9 (growth differentiation factor 9).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
18 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Chen et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gdf9 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary ovarian insufficiency 14 Alliance ?Premature ovarian failure 14 618014
Associated With gdf9 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017948 Transforming growth factor beta, conserved site
Domain IPR001839 Transforming growth factor-beta, C-terminal
Family IPR015615 Transforming growth factor-beta-related
Family IPR015617 Growth differentiation factor-9
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Cystine-knot cytokine Growth differentiation factor-9 Transforming growth factor beta, conserved site Transforming growth factor-beta, C-terminal Transforming growth factor-beta-related
UniProtKB:Q32PR5 418
UniProtKB:Q5MD90 418
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations