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Gene

cfh

ID
ZDB-GENE-050208-661
Name
complement factor H
Symbol
cfh Nomenclature History
Previous Names
  • im:7147412
  • si:ch211-207o17.2
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Is expressed in several structures, including digestive system; eye; fin; gill; and heart. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; atypical hemolytic-uremic syndrome; eye disease (multiple); hemolytic-uremic syndrome; and lupus nephritis. Orthologous to human CFH (complement factor H).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cfh Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
age related macular degeneration 4 Alliance {Macular degeneration, age-related, 4} 610698
basal laminar drusen Alliance Basal laminar drusen 126700
Complement factor H deficiency 609814
{Hemolytic uremic syndrome, atypical, susceptibility to, 1} 235400
Associated With cfh Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000436 Sushi/SCR/CCP domain
Homologous_superfamily IPR035976 Sushi/SCR/CCP superfamily
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations