Gene

rnasel2

ID
ZDB-GENE-050208-420
Name
ribonuclease like 2
Symbol
rnasel2 Nomenclature History
Previous Names
  • Dr-RNase2 (1)
  • RNase ZF-2 (1)
  • zf-rnase-2 (1)
  • si:ch211-139g14.6
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Exhibits ribonuclease activity. Involved in angiogenesis; defense response to Gram-negative bacterium; and defense response to Gram-positive bacterium. Human ortholog(s) of this gene implicated in diabetic retinopathy; myocardial infarction; neurodegenerative disease (multiple); and prostate cancer. Is expressed in gut; heart; intestine; and liver. Orthologous to several human genes including ANG (angiogenin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rnasel2 Human Ortholog
No data available
Associated With rnasel2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR023411 Ribonuclease A, active site
Domain IPR023412 Ribonuclease A-domain
Family IPR001427 Pancreatic ribonuclease
Homologous_superfamily IPR036816 Ribonuclease A-like domain superfamily
Domain Details Per Protein
Protein Length Pancreatic ribonuclease Ribonuclease A, active site Ribonuclease A-domain Ribonuclease A-like domain superfamily
UniProtKB:A5HAK1 150
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations