ZFIN ID: ZDB-GENE-050208-408
Gene Name: glutaminase 2b (liver, mitochondrial)
Gene Symbol: gls2b    Nomenclature History

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Previous Name: si:dkey-102c8.6

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have glutaminase activity. Predicted to be involved in glutamate biosynthetic process and glutamine catabolic process. Is expressed in intestine and liver. Orthologous to human GLS2 (glutaminase 2).
Genome Resources: Alliance (1),  Gene:556445 (1),  Ensembl(GRCz11):ENSDARG00000002917 (2)
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu455]
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa29725 Point Mutation Unknown Splice Site ENU
sa30726 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32379 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39358 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gls2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gls2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glutamine metabolic process (more)
    Molecular Function glutaminase activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gls2b-202 (1)    Ensembl 2244
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gls2b No data available
    MARKER RELATIONSHIPS
    gls2b Contained in: [BAC] DKEY-102C8 (1) (order this)
    gls2b Encodes: [EST] eu455 (1)
    [cDNA] MGC:162224 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001083825 (1) 2133 nt
    Genomic GenBank:BX324213 (1) 94824 nt
    Select Tool
    Polypeptide UniProtKB:Q1LXG0 (1) 627 aa
    Sequence Information (all 16)
    ORTHOLOGY for gls2b ( Chr: 22 )
    CITATIONS (21)