Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-041220-3
Gene Name: transferrin receptor 2
Gene Symbol: tfr2
Previous Name: zgc:123043
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. 2 from Fraenkel et al., 2009
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Hatching:Long-pec (48.0h-60.0h)
  liver
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 4 genotypes
Alleles: f4, f5, f6, f7
Knockdown reagents: MO1-tfr2 (1)
PHENOTYPE
Data: Fig. 3 from Fraenkel et al., 2009
Observed in: nucleate erythrocyte hemoglobin complex

Phenotype of Human Orthologue OMIM Phenotype ID
Hemochromatosis, type 3 604250
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component cellular_component (more)
Molecular Function peptidase activity (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003137 (1)
  • InterPro:IPR007365 (1)
  • InterPro:IPR007484 (1)
  • Pfam:PF02225 (1)
  • Pfam:PF04253 (1)
  • Pfam:PF04389 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM tfr2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    tfr2 Encodes: [cDNA] MGC:123043 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001009916 (1) 2352 bp
    Genomic RefSeq:NW_003336789 (1) 3784 bp Blast at Vega
    Polypeptide UniProtKB:Q5MPX2 (1) 783 aa
    Sequence Clusters UniGene:91716 (1)
    Sequence Information (all 18)
    OTHER tfr2 GENE PAGES
  • Gene:494476 (1)
  • MAPPING INFORMATION Unknown
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish tfr2  
    Human TFR2 7 (7q22)
  • OMIM:604720
  • Gene:7036
  • Mouse Tfr2 5 ( 76.57 cM)
  • MGI:1354956
  • Gene:50765
  • CITATIONS (10)