ZFIN ID: ZDB-GENE-041210-183
Gene Name: leptin b
Gene Symbol: lepb
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: si:dkey-21o22.1

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have hormone activity; involved in response to starvation; predicted to localize to the extracellular region; orthologous to human LEP (leptin).
GENE EXPRESSION
All Expression Data: 7 figures from 6 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
pd94 Indel Unknown Frameshift, Premature Stop TALEN
sa16807 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lepb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Obesity, morbid, due to leptin deficiency 614962
    DISEASE ASSOCIATED WITH lepb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to starvation (more)
    Cellular Component extracellular region (more)
    Molecular Function hormone activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000065 (1)
  • InterPro:IPR009079 (1)
  • Pfam:PF02024 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lepb-201 (1) 589
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lepb
    MARKER RELATIONSHIPS
    lepbContained in: [BAC] DKEY-21O22 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001030186 (1) 589bp
    Genomic GenBank:BX649263 (1) 143254bp
    Select Tool
    Polypeptide UniProtKB:C4WYH6 (1) 168aa
    Sequence Clusters UniGene:86770 (1)
    Sequence Information (all 9)
    OTHER lepb GENE PAGES
  • Alliance (1)
  • Gene:564348 (1)
  • VEGA:OTTDARG00000008208 (1)
  • Ensembl(GRCz11):ENSDARG00000045548 (2)
  • ORTHOLOGY for lepb (Chr: 4)
    CITATIONS (34)