ZFIN ID: ZDB-GENE-041114-68
Gene Name: Tp53rk binding protein
Gene Symbol: tprkb
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:101896

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to be involved in tRNA threonylcarbamoyladenosine modification; predicted to localize to the EKC/KEOPS complex, cytoplasm, and nucleus; orthologous to human TPRKB (TP53RK binding protein).
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
cl601 Small Deletion Exon 2 Frameshift, Premature Stop CRISPR
cl603 Indel Unknown Unknown CRISPR
Targeting reagents:
PHENOTYPE
Data: 4 figures from 2 publications
Observed in:
DISEASE ASSOCIATED WITH tprkb HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Galloway-Mowat syndrome 5 Galloway-Mowat syndrome 5 617731
DISEASE ASSOCIATED WITH tprkb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process tRNA threonylcarbamoyladenosine modification (more)
Cellular Component cytoplasm (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013926 (1)
  • InterPro:IPR036504 (1)
  • Pfam:PF08617 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tprkb-201 (1) 1049
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tprkb No data available
    MARKER RELATIONSHIPS
    tprkbContained in: [BAC] CH73-263O4 (1) (order this)
    tprkbEncodes: [cDNA] MGC:101896 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007373 (1) 1142bp
    Genomic GenBank:CU855579 (1) 75025bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8QN58 (1) 176aa
    Sequence Clusters UniGene:91625 (1)
    Sequence Information (all 14)
    OTHER tprkb GENE PAGES
  • Alliance (1)
  • Gene:492501 (1)
  • VEGA:OTTDARG00000035913 (1)
  • Ensembl(GRCz11):ENSDARG00000014941 (2)
  • ORTHOLOGY for tprkb (Chr: 4)
    CITATIONS (20)