ZFIN ID: ZDB-GENE-041111-205
Gene Name: centromere protein F
Gene Symbol: cenpf    Nomenclature History

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Previous Names: im:7140452, im:7144238, im:7154719 (1), im:7156761, si:ch211-152h14.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have dynein complex binding activity; protein homodimerization activity; and transcription factor binding activity. Involved in animal organ development and cilium assembly. Is expressed in proliferative region. Human ortholog(s) of this gene implicated in Stromme syndrome. Orthologous to human CENPF (centromere protein F).
Genome Resources: Alliance (1),  Gene:497403 (1),  Ensembl(GRCz11):ENSDARG00000055133 (2)
GENE EXPRESSION
All Expression Data: 15 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7144238]
  6 figures (10 images) from Thisse et al., 2004 [IMAGE:7140452]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7156761]
  6 figures (10 images) from Thisse et al., 2004 [IMAGE:7154719]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10281 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11610 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12055 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12296 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23121 Point Mutation Unknown Missense, Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23122 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa28887 Point Mutation Unknown Splice Site, Premature Stop ENU
    sa28888 Point Mutation Unknown Premature Stop ENU
    sa36461 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36462 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39168 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cenpf N/A 1
    MO2-cenpf N/A 1
    DISEASE ASSOCIATED WITH cenpf HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Stromme syndrome Alliance Stromme syndrome 243605
    DISEASE ASSOCIATED WITH cenpf VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cilium assembly (more)
    Cellular Component cellular_component (more)
    Molecular Function dynein complex binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cenpf-201 (1)    Ensembl 9162
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cenpf No data available
    MARKER RELATIONSHIPS
    cenpf Contained in: [BAC] CH211-152H14 (1)
    cenpf Encodes: [EST] IMAGE:7140452 (1), IMAGE:7144238 (1), IMAGE:7154719 (1), IMAGE:7156761 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_002665215 (1)
    Genomic GenBank:BX936381 (1) 156270 nt
    Select Tool
    Polypeptide UniProtKB:F1Q7X5 (1) 2708 aa
    Sequence Information (all 24)
    ORTHOLOGY for cenpf ( Chr: 17 )
    CITATIONS (18)