Gene

ppip5k2

ID
ZDB-GENE-091204-125
Name
diphosphoinositol pentakisphosphate kinase 2
Symbol
ppip5k2 Nomenclature History
Previous Names
  • im:7137778
  • si:dkey-117i20.1
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have diphosphoinositol-pentakisphosphate kinase activity; inositol heptakisphosphate kinase activity; and inositol hexakisphosphate kinase activity. Predicted to be involved in inositol metabolic process and inositol phosphate biosynthetic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 100. Orthologous to human PPIP5K2 (diphosphoinositol pentakisphosphate kinase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppip5k2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 100 Alliance Deafness, autosomal recessive 100 618422
Associated With ppip5k2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR033379 Histidine acid phosphatase active site
Domain IPR040557 VIP1, N-terminal
Family IPR000560 Histidine phosphatase superfamily, clade-2
Family IPR037446 Histidine acid phosphatase, VIP1 family
Homologous_superfamily IPR029033 Histidine phosphatase superfamily
Domain Details Per Protein
Protein Length Histidine acid phosphatase active site Histidine acid phosphatase, VIP1 family Histidine phosphatase superfamily Histidine phosphatase superfamily, clade-2 VIP1, N-terminal
UniProtKB:E7F712 1303
UniProtKB:F1RCW1 187
UniProtKB:E9QG38 1224
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations