Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040801-149
Gene Name: ATG5 autophagy related 5 homolog (S. cerevisiae)
Gene Symbol: atg5
Previous Names: apg5l (1), zgc:100934 (1)
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7145909]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 4 (96.0h-120.0h)
  eye, floor plate, forebrain, head (all 13) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa22749
Knockdown reagents: MO1-atg5 (1), MO2-atg5 (1), MO3-atg5 (1)
PHENOTYPE
Data: Fig. 3 from Hu et al., 2011
Observed in: blood, common cardinal vein, embryo development, extension (all 14) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process nervous system development (more)
Cellular Component cytoplasm (more)
Molecular Function CONTRIBUTES_TO Atg8 ligase activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007239 (1)
  • Pfam:PF04106 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atg5-001 (1) 2264
    atg5-002 (1) 2222
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-atg5 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atg5 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atg5 Contained in: [BAC] DKEY-11F5 (1)
    atg5 Encodes: [EST] IMAGE:7145909 (1) (order this)
    [cDNA] MGC:100934 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001009914 (1) 2279 bp
    Genomic GenBank:AL928573 (1) 244471 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1RDC0 (1) 275 aa
    Sequence Clusters UniGene:12686 (1)
    Sequence Information (all 18)
    OTHER atg5 GENE PAGES
  • Gene:494180 (1)
  • VEGA:OTTDARG00000034037 (1)
  • Ensembl(Zv9):ENSDARG00000023396 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish atg5 16  
    Human ATG5 6 (6q21)
  • OMIM:604261
  • Gene:9474
  • Orthology Details
    CITATIONS (20)