ZFIN ID: ZDB-GENE-040801-149
Gene Name: ATG5 autophagy related 5 homolog (S. cerevisiae)
Gene Symbol: atg5
Previous Names: apg5l (1), zgc:100934 (1)
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7145909]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 4 (96.0h-120.0h)
  eye, floor plate, forebrain, head (all 13) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-atg5 (1), MO2-atg5 (1), MO3-atg5 (1)

Allele Type Mutagen Suppliers
sa22749 Point Mutation ENU
PHENOTYPE
Data: Fig. 3 from Hu et al., 2011
Observed in: blood, common cardinal vein, embryo development, extension (all 14) expand
DISEASE ASSOCIATED WITH atg5 HUMAN ORTHOLOG No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process nervous system development (more)
Cellular Component cytoplasm (more)
Molecular Function CONTRIBUTES_TO Atg8 ligase activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007239 (1)
  • Pfam:PF04106 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atg5-001 (1) 2264
    atg5-002 (1) 2222
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-atg5 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atg5 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atg5 Contained in: [BAC] DKEY-11F5 (1) (order this)
    atg5 Encodes: [EST] IMAGE:7145909 (1) (order this)
    [cDNA] MGC:100934 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001009914 (1) 2279 bp
    Genomic GenBank:AL928573 (1) 244471 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1RDC0 (1) 275 aa
    Sequence Clusters UniGene:12686 (1)
    Sequence Information (all 18)
    OTHER atg5 GENE PAGES
  • Gene:494180 (1)
  • VEGA:OTTDARG00000034037 (1)
  • Ensembl(Zv9):ENSDARG00000023396 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish atg5 16  
    Human ATG5 6 (6q21)
  • OMIM:604261
  • Gene:9474
  • Orthology Details
    CITATIONS (23)