Gene

crk

ID

ZDB-GENE-040801-148

Name

v-crk avian sarcoma virus CT10 oncogene homolog

Symbol

crk Nomenclature History

Previous Names

fb34h10
fc05a01
fi19g05
wu:fb34h10
wu:fc05a01
wu:fc54a04
wu:fi19g05
zgc:100936 (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Involved in myoblast fusion. Orthologous to human CRK (CRK proto-oncogene, adaptor protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7146003 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With crk Human Ortholog

No data available

Associated With crk Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000980	SH2 domain
Domain	IPR001452	SH3 domain
Domain	IPR035457	CRK, N-terminal SH3 domain
Domain	IPR035458	CRK, C-terminal SH3 domain
Homologous_superfamily	IPR036028	SH3-like domain superfamily
Homologous_superfamily	IPR036860	SH2 domain superfamily

Domain Details Per Protein

Protein	Length	CRK, C-terminal SH3 domain	CRK, N-terminal SH3 domain	SH2 domain	SH2 domain superfamily	SH3 domain	SH3-like domain superfamily
UniProtKB:Q6DEM2 InterPro	311

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	crk-201 (1) Ensembl	Havana	3346 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations