Gene

sypb

ID
ZDB-GENE-040718-205
Name
synaptophysin b
Symbol
sypb Nomenclature History
Previous Names
  • zgc:136469
  • zgc:92837
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have syntaxin-1 binding activity. Involved in glial cell development and retina development in camera-type eye. Predicted to localize to presynaptic active zone and synaptic vesicle membrane. Is expressed in central nervous system; lateral wall spinal cord; midbrain; retinal inner plexiform layer; and retinal outer plexiform layer. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human SYP (synaptophysin).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Charlton-Perkins et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sypb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
non-syndromic X-linked intellectual disability Alliance Mental retardation, X-linked 96 300802
Associated With sypb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR008253 Marvel domain
Family IPR001285 Synaptophysin/synaptoporin
Family IPR028714 Synaptophysin
Domain Details Per Protein
Protein Length Marvel domain Synaptophysin Synaptophysin/synaptoporin
UniProtKB:Q6DGP1 261
UniProtKB:B0S6H7 261
UniProtKB:Q4JQP7 297
UniProtKB:B0S6H6 297
UniProtKB:A4FVL5 240
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations