ZFIN ID: ZDB-GENE-040426-2903
Gene Name: F-box and WD repeat domain containing 11b
Gene Symbol: fbxw11b    Nomenclature History

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Previous Names: btrc2, fbxw11, wu:fa12e12, wu:fb11f03, zgc:63728

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have protein dimerization activity. Involved in sprouting angiogenesis. Predicted to localize to SCF ubiquitin ligase complex. Orthologous to several human genes including FBXW11 (F-box and WD repeat domain containing 11).
Genome Resources: Alliance (1),  Gene:406825 (1),  Ensembl(GRCz11):ENSDARG00000017230 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63728]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
u5010 Small Deletion Unknown Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-fbxw11b 1
MO1-fbxw11b N/A 1
MO2-fbxw11b N/A 1
MO3-fbxw11b N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH fbxw11b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental, jaw, eye, and digital syndrome 618914
DISEASE ASSOCIATED WITH fbxw11b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process sprouting angiogenesis (more)
Cellular Component SCF ubiquitin ligase complex (more)
Molecular Function protein dimerization activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA fbxw11b-202 (1)    Ensembl 2496
ncRNA fbxw11b-002 (1)    Ensembl 765
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM fbxw11b No data available
MARKER RELATIONSHIPS
fbxw11b Contained in: [BAC] DKEY-106M10 (1) (order this)
fbxw11b Encodes: [EST] fa12e12 (1), fb11f03 (1)
[cDNA] MGC:63728 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_213504 (1) 2534 nt
Genomic GenBank:BX465186 (1) 247227 nt Blast at MegaBLAST
Polypeptide UniProtKB:A0A2R8RWN9 (1) 534 aa
Sequence Information (all 17)
ORTHOLOGY for fbxw11b ( Chr: 10 )
CITATIONS (23)