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ZIRC
ZFIN ID: ZDB-GENE-040426-2495
Gene Name: family with sequence similarity 53 member B
Gene Symbol: fam53b
Sequence Ontology ID : SO:0000704

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Previous Names: smp (1), simplet (1), wu:fo86c04, zgc:55329, zgc:77156

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in several processes, including axon extension; fin regeneration; and protein import into nucleus. Localizes to the nucleus. Orthologous to human FAM53B (family with sequence similarity 53  ...
GENE EXPRESSION
All Expression Data: 7 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55329]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8888 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH fam53b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fam53b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axon extension (more)
    Cellular Component nucleus (more)
    Molecular Function molecular_function (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR029356 (1)
  • Pfam:PF15242 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA fam53b-003 (1) 542
    mRNA fam53b-201 (1) 1700
    aberrant processed transcript fam53b-203 (1) 1585
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM fam53b No data available
    MARKER RELATIONSHIPS
    fam53bContained in: [BAC] DKEY-68E16 (1) (order this)
    fam53bEncodes: [EST] fo86c04 (1)
    [cDNA] MGC:55329 (1) (order this), MGC:77156 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007187 (1) 1740bp
    Genomic GenBank:AL953868 (1) 182445bp
    Select Tool
    Polypeptide UniProtKB:F1QN48 (1) 379aa
    Sequence Clusters UniGene:78254 (1)
    Sequence Information (all 18)
    ORTHOLOGY for fam53b (Chr: 12)
    CITATIONS (25)