Gene

dusp8a

ID

ZDB-GENE-040426-1842

Name

dual specificity phosphatase 8a

Symbol

dusp8a Nomenclature History

Previous Names

zgc:77593

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have MAP kinase tyrosine/serine/threonine phosphatase activity; mitogen-activated protein kinase binding activity; and protein tyrosine/threonine phosphatase activity. Predicted to be involved in inactivation of MAPK activity; peptidyl-threonine dephosphorylation; and peptidyl-tyrosine dephosphorylation. Predicted to localize to cytosol. Is expressed in nervous system and neural rod. Orthologous to human DUSP8 (dual specificity phosphatase 8).

Genome Resources

Note

None

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

MGC:77593 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dusp8a Human Ortholog

No data available

Associated With dusp8a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000387	Tyrosine specific protein phosphatases domain
Domain	IPR001763	Rhodanese-like domain
Domain	IPR020422	Dual specificity protein phosphatase domain
Family	IPR008343	Mitogen-activated protein (MAP) kinase phosphatase
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like
Homologous_superfamily	IPR036873	Rhodanese-like domain superfamily