Gene
dusp8a
- ID
- ZDB-GENE-040426-1842
- Name
- dual specificity phosphatase 8a
- Symbol
- dusp8a Nomenclature History
- Previous Names
-
- zgc:77593
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have MAP kinase tyrosine/serine/threonine phosphatase activity; mitogen-activated protein kinase binding activity; and protein tyrosine/threonine phosphatase activity. Predicted to be involved in inactivation of MAPK activity; peptidyl-threonine dephosphorylation; and peptidyl-tyrosine dephosphorylation. Predicted to localize to cytosol. Is expressed in nervous system and neural rod. Orthologous to human DUSP8 (dual specificity phosphatase 8).
- Genome Resources
- Note
- None
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77593 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
Domain | IPR000387 | Tyrosine specific protein phosphatases domain |
Domain | IPR001763 | Rhodanese-like domain |
Domain | IPR020422 | Dual specificity protein phosphatase domain |
Family | IPR008343 | Mitogen-activated protein (MAP) kinase phosphatase |
Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
Homologous_superfamily | IPR036873 | Rhodanese-like domain superfamily |
Domain Details Per Protein
Protein | Length | Dual specificity protein phosphatase domain | Mitogen-activated protein (MAP) kinase phosphatase | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase-like | Rhodanese-like domain | Rhodanese-like domain superfamily | Tyrosine specific protein phosphatases domain |
---|---|---|---|---|---|---|---|---|
UniProtKB:Q6P3L8
|
629 | |||||||
UniProtKB:F1QVZ9
|
629 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
dusp8a-201
(1)
|
3407 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl