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ZIRC
ZFIN ID: ZDB-GENE-040426-1451
Gene Name: frizzled class receptor 6
Gene Symbol: fzd6    Nomenclature History

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Previous Names: zgc:65879, zgc:77440

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have Wnt-activated receptor activity. Involved in angiogenesis and embryonic cranial skeleton morphogenesis. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 10. Is expressed in head; nervous system; and pectoral fin. Orthologous to human FZD6 (frizzled class receptor 6).
Genome Resources: Alliance (1),  Gene:393533 (1),  Ensembl(GRCz11):ENSDARG00000104874 (1)
GENE EXPRESSION
All Expression Data: 6 figures from 5 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:77440]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22966 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-fzd6 N/A 1
    MO2-fzd6 N/A 2
    MO3-fzd6 N/A 1
    DISEASE ASSOCIATED WITH fzd6 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    nonsyndromic congenital nail disorder 10 Alliance Nail disorder, nonsyndromic congenital, 10, (claw-shaped nails) 614157
    DISEASE ASSOCIATED WITH fzd6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function transmembrane signaling receptor activity (more)
    GO Terms (all 12)
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fzd6 No data available
    MARKER RELATIONSHIPS
    fzd6 Encodes: [cDNA] MGC:65879 (1) (order this), MGC:77440 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200561 (1) 4028 bp
    Genomic GenBank:CABZ01088508 (1) 3921 bp
    Polypeptide UniProtKB:A0A0G2L696 (1) 617 aa
    Sequence Clusters UniGene:121084 (1)
    Sequence Information (all 20)
    ORTHOLOGY for fzd6 ( Chr: 16 )
    CITATIONS (28)