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ZIRC
ZFIN ID: ZDB-GENE-040220-2
Gene Name: toll-like receptor 18
Gene Symbol: tlr18    Nomenclature History

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Previous Name: TIR1.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to be involved in inflammatory response and toll-like receptor signaling pathway. Predicted to localize to the integral component of plasma membrane. Is expressed in blood; brain; integument; liver; and pleuroperitoneal region.
Genome Resources: Alliance (1),  Gene:403133 (1),  Ensembl(GRCz11):ENSDARG00000040249 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012918Tg Transgenic Insertion Unknown Unknown DNA
la012919Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa471 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36169 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tlr18 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tlr18 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 6)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tlr18-202 (1)    Ensembl 2777
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tlr18 No data available
    MARKER RELATIONSHIPS
    tlr18 Contained in: [BAC] CH211-113G11 (1) (order this)
    tlr18 Encodes: [cDNA] MGC:194171 (1) (order this), MGC:195267 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001089350 (1) 2723 bp
    Genomic GenBank:AL954306 (1) 169830 bp
    Select Tool
    Polypeptide UniProtKB:A3KH14 (1) 854 aa
    Sequence Clusters UniGene:89702 (1)
    Sequence Information (all 21)
    ORTHOLOGY for tlr18 ( Chr: 16 )
    CITATIONS (32)