ZFIN ID: ZDB-GENE-040219-7
Gene Name: toll-like receptor 3
Gene Symbol: tlr3
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:123006

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have double-stranded RNA binding activity and transmembrane signaling receptor activity; involved in response to bacterium and response to virus; predicted to localize to the integral  ...
GENE EXPRESSION
All Expression Data: 22 figures from 13 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu558]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa39587 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tlr3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acquired immunodeficiency syndrome {HIV1 infection, resistance to} 609423
    {Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 2} 613002
    DISEASE ASSOCIATED WITH tlr3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to bacterium (more)
    Cellular Component integral component of membrane (more)
    Molecular Function protein binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000157 (1)
  • InterPro:IPR000483 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR003591 (1)
  • InterPro:IPR026906 (1)
  • InterPro:IPR027173 (1)
  • InterPro:IPR032675 (1)
  • InterPro:IPR035897 (1)
  • PROSITE:PS50104 (1)
  • PROSITE:PS51450 (1)
  • Pfam:PF13306 (1)
  • Pfam:PF13676 (1)
  • Pfam:PF13855 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tlr3-001 (1) 3161
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tlr3 No data available
    MARKER RELATIONSHIPS
    tlr3Contained in: [BAC] DKEYP-11A2 (1)
    tlr3Encodes: [EST] eu558 (1)
    [cDNA] MGC:123006 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001013269 (1) 3165bp
    Genomic GenBank:CR774194 (1) 160120bp
    Select Tool
    Polypeptide UniProtKB:B8JIL3 (1) 903aa
    Sequence Clusters UniGene:82491 (1)
    Sequence Information (all 19)
    OTHER tlr3 GENE PAGES
  • Alliance (1)
  • Gene:403126 (1)
  • VEGA:OTTDARG00000019501 (1)
  • ORTHOLOGY for tlr3 (Chr: 1)
    CITATIONS (66)