ZFIN ID: ZDB-GENE-031116-52
Gene Name: integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Gene Symbol: itga5
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: bfe (1), before eight (1), sb:cb665, wu:fe02h07

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits fibronectin binding activity and protein heterodimerization activity; involved in several processes, including animal organ development, cell migration involved in sprouting angiogenesis,  ...
GENE EXPRESSION
All Expression Data: 21 figures from 13 publications
Directly Submitted Expression Data: 6 figures (17 images) from Thisse et al., 2001 [cb665]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b926 Point Mutation Unknown Missense ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • itga5_unspecified Unspecified Unknown Unknown
    kt293 Small Deletion Unknown Unknown ENU
    kt451 Point Mutation Unknown Unknown ENU
    kt664 Unknown Unknown Unknown ENU
    la014415Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la022674Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la022675Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la022676Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13598 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13837 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44025 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tbfe1 Point Mutation Unknown Unknown
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tbfe2 Point Mutation Unknown Unknown
    Targeting reagents:
    PHENOTYPE
    Data: 15 figures from 7 publications
    Observed in:
    DISEASE ASSOCIATED WITH itga5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH itga5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic viscerocranium morphogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function protein heterodimerization activity (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000413 (1)
  • InterPro:IPR013517 (1)
  • InterPro:IPR013519 (1)
  • InterPro:IPR013649 (1)
  • InterPro:IPR018184 (1)
  • InterPro:IPR028994 (1)
  • InterPro:IPR032695 (1)
  • PROSITE:PS00242 (1)
  • PROSITE:PS51470 (1)
  • Pfam:PF01839 (1)
  • Pfam:PF08441 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA itga5-002 (1) 676
    mRNA itga5-201 (1) 5405
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM itga5
    MARKER RELATIONSHIPS
    itga5Contained in: [BAC] DKEY-27M20 (1) (order this), DKEY-32G6 (1) (order this), DKEY-220D15 (1) (order this)
    itga5Encodes: [EST] cb665 (1) (order this), fe02h07 (1)
    [cDNA] MGC:195021 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001004288 (1) 3737bp
    Genomic GenBank:CR293512 (1) 127255bp
    Select Tool
    Polypeptide UniProtKB:Q5I2A9 (1) 1053aa
    Sequence Clusters UniGene:80637 (1)
    Sequence Information (all 23)
    OTHER itga5 GENE PAGES
  • Alliance (1)
  • Gene:386787 (1)
  • VEGA:OTTDARG00000021279 (1)
  • Ensembl(GRCz11):ENSDARG00000006353 (2)
  • ORTHOLOGY for itga5 (Chr: 23)
    CITATIONS (59)