Gene

itga5

ID
ZDB-GENE-031116-52
Name
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Symbol
itga5 Nomenclature History
Previous Names
  • bfe (1)
  • before eight (1)
  • sb:cb665
  • wu:fe02h07
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Exhibits fibronectin binding activity and protein heterodimerization activity. Involved in several processes, including camera-type eye development; cell migration involved in sprouting angiogenesis; and chordate embryonic development. Predicted to localize to integrin complex. Is expressed in several structures, including cardiovascular system; ectoderm; head; mesoderm; and somite. Orthologous to human ITGA5 (integrin subunit alpha 5).
Genome Resources
Note
None
Expression
All Expression Data
22 figures from 14 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
18 figures from 9 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With itga5 Human Ortholog
No data available
Associated With itga5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018184 Integrin alpha chain, C-terminal cytoplasmic region, conserved site
Domain IPR013649 Integrin alpha-2
Family IPR000413 Integrin alpha chain
Homologous_superfamily IPR028994 Integrin alpha, N-terminal
Homologous_superfamily IPR032695 Integrin domain superfamily
Repeat IPR013517 FG-GAP repeat
Repeat IPR013519 Integrin alpha beta-propellor
Domain Details Per Protein
Protein Length FG-GAP repeat Integrin alpha-2 Integrin alpha beta-propellor Integrin alpha chain Integrin alpha chain, C-terminal cytoplasmic region, conserved site Integrin alpha, N-terminal Integrin domain superfamily
UniProtKB:Q5I2A9 1053
UniProtKB:B3DJJ0 1035
UniProtKB:Q6QAF3 1035
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations