ZFIN ID: ZDB-GENE-030616-550
Gene Name: glutaminase b
Gene Symbol: glsb    Nomenclature History

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Previous Names: gls, si:dz87i4.2, wu:fa97e05 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have glutaminase activity. Predicted to be involved in glutamate biosynthetic process and glutamine catabolic process. Is expressed in brain; intestinal bulb; pectoral fin; and swim bladder. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy. Orthologous to human GLS (glutaminase).
Genome Resources: Alliance (1),  Gene:564746 (1),  Ensembl(GRCz11):ENSDARG00000040705 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH glsb HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Epileptic encephalopathy, early infantile, 71 618328
Global developmental delay, progressive ataxia, and elevated glutamine 618412
?Infantile cataract, skin abnormalities, glutamate excess, and impaired intellectual development 618339
DISEASE ASSOCIATED WITH glsb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process glutamine metabolic process (more)
Molecular Function glutaminase activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA glsb-202 (1)    Ensembl 669
glsb-203 (1)    Ensembl 1618
glsb-204 (1)    Ensembl 4343
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM glsb No data available
MARKER RELATIONSHIPS
glsb Contained in: [BAC] CH211-196J1 (1)
[PAC] BUSM1-87I4 (1)
glsb Encodes: [EST] fa97e05
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_005167899 (1)
Genomic GenBank:BX649377 (1) 217898 nt Blast at MegaBLAST
Polypeptide UniProtKB:F1RDU2 (1) 566 aa
Sequence Information (all 35)
ORTHOLOGY for glsb ( Chr: 9 )
CITATIONS (23)