Gene

epb41l5

ID
ZDB-GENE-030616-450
Name
erythrocyte membrane protein band 4.1 like 5
Symbol
epb41l5 Nomenclature History
Previous Names
  • moe
  • mosaic eyes
  • si:dz104f18.2
  • si:dz104f18.3
  • si:dz37o5.2
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable cytoskeletal protein binding activity. Acts upstream of or within several processes, including animal organ development; maintenance of epithelial cell apical/basal polarity; and positive regulation of Notch signaling pathway. Located in bicellular tight junction. Part of protein-containing complex. Is expressed in integument; nervous system; and pronephros. Used to study proteinuria. Orthologous to human EPB41L5 (erythrocyte membrane protein band 4.1 like 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
15 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With epb41l5 Human Ortholog
No data available
Associated With epb41l5 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019747 FERM conserved site
Domain IPR000299 FERM domain
Domain IPR014847 FERM adjacent (FA)
Domain IPR018979 FERM, N-terminal
Domain IPR018980 FERM, C-terminal PH-like domain
Domain IPR019748 FERM central domain
Domain IPR019749 Band 4.1 domain
Family IPR000798 Ezrin/radixin/moesin-like
Family IPR030694 Band 4.1-like protein 5
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR014352 FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
Homologous_superfamily IPR035963 FERM superfamily, second domain
Domain Details Per Protein
Protein Length Band 4.1 domain Band 4.1-like protein 5 Ezrin/radixin/moesin-like FERM/acyl-CoA-binding protein superfamily FERM adjacent (FA) FERM central domain FERM conserved site FERM, C-terminal PH-like domain FERM domain FERM, N-terminal FERM superfamily, second domain PH-like domain superfamily Ubiquitin-like domain superfamily
UniProtKB:F1QVV9 461
UniProtKB:Q6NYK4 772
UniProtKB:Q6PNC5 776
UniProtKB:Q8JFS8 60
UniProtKB:Q8AW26 218
UniProtKB:Q8AW25 377
UniProtKB:A0A2R8QU80 453
UniProtKB:F6NJ58 783
UniProtKB:Q8AWY0 245
UniProtKB:F1Q9F0 772
UniProtKB:A0A2R8QDM4 773
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-epb41l5 polyclonal Rabbit
  • IHC
  • WB
2
Ab2-epb41l5 polyclonal Guinea pig
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations