ZFIN ID: ZDB-GENE-030131-9858
Gene Name: PPARG related coactivator 1
Gene Symbol: pprc1    Nomenclature History

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Previous Names: cb478 (1), sb:cb478, wu:fb72d09, wu:fj86g08

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have nuclear receptor transcription coactivator activity and transcription factor binding activity. Predicted to be involved in positive regulation of DNA-binding transcription factor activity and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including alar plate midbrain region; anterior axial hypoblast; brain; immature eye; and mesoderm. Orthologous to human PPRC1 (PPARG related coactivator 1).
Genome Resources: Alliance (1),  Gene:100002463 (1),  Ensembl(GRCz11):ENSDARG00000090337 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010147Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22245 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35433 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-pprc1
    2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pprc1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pprc1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of DNA-binding transcription factor activity (more)
    Cellular Component nucleus (more)
    Molecular Function nucleic acid binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pprc1-201 (1)    Ensembl 4265
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pprc1 No data available
    MARKER RELATIONSHIPS
    pprc1 Contained in: [BAC] DKEY-52K1 (order this)
    pprc1 Encodes: [EST] cb478 (1) (order this), fb72d09 (1), fj86g08 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_001338200 (1) 4211 nt
    Genomic GenBank:CR792443 (1) 217981 nt Blast at MegaBLAST
    Polypeptide UniProtKB:E7F4W0 (1) 1220 aa
    Sequence Information (all 15)
    ORTHOLOGY for pprc1 ( Chr: 13 )
    CITATIONS (29)